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Gaining royal favour and high honours and distinction from an early date, bearers of the Williams name have stamped an indelible mark on the pages of the historical record.
From the diverse worlds of politics and literature to the stage, sport and music, some have achieved fame and others notoriety.
The colourful drama that is their stirring lives and times is recorded here.
Born in the hamlet of Gwynfe, Carmarthenshire in 1840, John Williams, more formally known as Sir John Williams, 1st Baronet, was not only a physician to Queen Victoria but also a principal founder of the National Library of Wales, in Aberystwyth.
The son of a Welsh Congregational minister, he was raised to his baronetcy by a grateful Queen Victoria in 1894, while he donated his vast collection of manuscripts, books and prints on Celtic matters as the library's 'foundation collection.'
In addition to his royal duties and practice as an obstetric surgeon in London, he was also the driving force behind a major campaign in his native Wales to combat tuberculosis.
He died in 1926, while a book published in 2005, Uncle Jack, makes the bizarre claim that he had in fact been the elusive Jack the Ripper, responsible for the gruesome slaying of five women in the Whitechapel area of London in 1888.
Written by one of his alleged descendants, Tony (Michael Anthony) Williams and co-authored by Humphrey Price, the book claims that all the victims were known to the surgeon and that he killed and mutilated them in a horrific attempt to research the causes of infertility.